Heterologous Expression systems are tools to find out whether a particular gene produces mRNA and/or protein and whether the protein produced is functional or defective. In these systems, we use the expression vectors in which cDNA of the gene of interest is clonned along with suitable promoter. When this gene is expressed through transcription by the formation of mRNA, then the resultant protein is formed by translation of mRNA.
大腸菌やバキュロなど普通の発現系のことね。つまり、人の遺伝子を人で発現させる系はhomologous expression system. その遺伝子を大腸菌や昆虫細胞などで発現させる系はheterologous expression system ってこと。heterologousっていうからなんか特別なものかと思ったのになぁというひとのために。
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